Thyroid hormones (T3 and T4) affect every cell and all the organs in the body by regulating the rate at which the body uses energy. This affects weight loss or weight gain and is called the metabolic rate. Thyroid hormones impact metabolism, growth, and development of organs and body tissues, they also affect your heart rate. The thyroid receptors belong to the superfamily of nuclear hormone receptors. Let’s dive into the functions of different thyroid hormones. T4 is the main thyroid hormone, which is high in hyperthyroidism or too much T4 medication. It can be low for untreated hypothyroidism or those who take T3 medication only. Reverse T3 is a form of deactivated T4, which is high in those with inflammatory conditions. Instead of creating T3, your body starts to create reverse T3 due to inflammation, toxicity, poor gut health, and sleep deprivation, which blocks the function of T3 leading to a decreased metabolism. Thyroid hormones and more specifically, T3, which is the active thyroid hormone, controls gene expression by binding on the thyroid receptors. Thyroid hormones trigger mitochondrial protein synthesis and increase total mitochondrial volume, which is directly linked to energy production and metabolism. T3 helps deliver oxygen and energy to all the body cells, its effects on target tissues are roughly four times more potent than those of T4. The number of receptors on a target cell can increase or decrease in response to hormone activity. T4 and T3 circulate almost entirely bound to specific transport proteins. If the levels of these transport proteins changes, there can be changes in how much bound T4 and T3 is measured. The “free” T4 or T3 is the hormone that is unbound and able to enter and affect the body tissues.
Reverse T3 is a biologically inactive protein that is structurally very similar to T3, but the iodine atoms are placed in different locations. Reverse T3 is created by degradation of the T4 under specific circumstances like high stress, starvation, and hepatic dysfunction and severe infections, therefore measuring this non active thyroid hormone gives a more complete picture of what is happening within the body that is contributing to thyroid dysfunction. It appears that reverseT3 can be elevated when the body is undergoing a crisis. Interestingly, serum reverse T3 was also significantly higher in diabetics than a nondiabetic population while serum T4 and TSH were within normal range. Once the diabetic patients received treatment, not only the blood glucose levels improve so as reverse T3 levels. Some studies suggest that those with hyperthyroidism have a higher reverse T3/T3 ratio than those with hypothyroidism, this indicates it can be a more sensitive marker for evaluating thyroid dysfunction and overall thyroid health than T4 and T3 alone.There are many medications that can affect thyroid function testing, and how to boost your thyroid function naturally? please check my new video.
- To book a healing session, please click here.
- To book a reading session, please click here.
- To book a TCM treatment, please click here.
- To book a group session for a variety of topics, please click here.
No comments:
Post a Comment