The low-fat recommendation has been around for a few decades, but cholesterol levels and heart disease rates have gone in the opposite direction since that time. In the two decades following that recommendation, the prevalence of obesity, Type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) have risen to new heights. It turned out that even-chain saturated fatty acids such as C16:0 are pro-inflammatory and are associated with increased risk of metabolic syndrome and heart disease, while odd-chain saturated fatty acids such as C15:0 regulate immune responses and are associated with better metabolic and heart health.
Dietary odd-chain saturated fatty acids (OCFAs) are present in trace levels in dairy fat and some meat products. Higher concentrations of OCFAs in the body, especially pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) are associated with lower risks of cardiovascular diseases. Studies have shown that higher dietary intake of OCFAs and higher circulating levels of OCFAs in the blood are associated with lower risks of obesity, cardiovascular disease, chronic inflammation, type-2 diabetes, metabolic syndrome, nonalcoholic fatty liver disease (NAFLD), and all-cause mortality.
Pentadecanoic acid (C15:0) is an essential odd-chain saturated fatty acid with broad activities that protect cardiovascular, metabolic, immune, and liver health. C15:0 activates AMPK and inhibits mTOR, both of which are core components of the human longevity pathway. C15:0 also helps repair mitochondrial function and benefits the endocannabinoid system for stabilizing metabolism, mood, and sleep patterns. It also reduces proinflammatory and profibrotic states in the human cells. C17:0 also has these effects but to a lesser degree.
A recent clinical trial has reported promising results about C15:0 supplementation in improving metabolic health and addressing a newly discovered condition known as Cellular Fragility Syndrome, which is a condition defined by a deficiency in C15:0. This deficiency affects cell membrane stability and increases susceptibility to ferroptosis – a form of cell death associated with the peroxidation of fragile fatty acids in cell membranes. Ferroptosis is related to various aging-related conditions, such as type 2 diabetes, cardiovascular disease, and nonalcoholic fatty liver disease (NAFLD). The study published in The Journal of Nutrition demonstrates that supplementing with C15:0 can effectively raise C15:0 levels in the blood, which improves liver function and red blood cell health.
NAFLD has become a significant public health concern and affects one in three individuals globally including one in ten children. The disease can progress to severe liver inflammation and cirrhosis, making it a leading cause of liver cancer and also contributing to cardiovascular mortality. Research has demonstrated that C15:0 supports healthy LDL cholesterol levels, improves the gut microbiome, and reduces liver fat. C-15:0 improves the stability of our cellular membranes, boosts mitochondrial function, and increases ATP-generating capabilities. Studies have shown that C15:0 can improve mitochondria function by increasing ATP production by 350%. our bodies use C15:0 to make a metabolite called pentadecanoylcarnitine (PDC). PDC is a newly discovered endocannabinoid that activates key cannabinoid receptors (CB1 and CB2) to calm the mood, improve sleep, and reduce joint pain.
Omega fatty acids such as omega-3 are polyunsaturated fatty acids, which are highly susceptible to lipid peroxidation in the bottle and our body. In comparison, C15:0 is a stable fatty acid that is resistant to oxidation and better protects our long-term health at the cellular level.
Here are some amazing health benefits of C15:0:
+ Reverses mitochondrial dysfunction by restoring energy-generating pathways.
+ Strengthens cardiovascular and immune systems by regulating immune responses.
+ Naturally activates receptors regulating metabolism, immunity, mood, sleep, and energy.
+ Strengthens body cells against age-related breakdown.
+ Reduces inflammation by turning down pro-inflammatory cytokines.
+ Promotes healthier skin and hair.
Foods rich in C15:0 include dairy products like whole milk, butter, cheese, cream, beef, bison, and lamb.
By the way, I am offering a talk on September 12th at the Art Center in Parksville. The topic is "How to Decalcify Your Pineal Gland and Raise Your Vibration for Ascension". Here are some highlights of my talk:
- The connection of the pineal gland and crystalline body and DNA upgrade.
- Why is the pineal gland the gateway to higher realms and ascension?
- What is the scientific evidence that the pineal gland is defined as the 3rd eye?
- Why is the pineal gland considered a Master Gland and what is its role in our physical health, emotional well-being, and vibration?
- What is pineal gland calcification and how to decalcify the pineal gland naturally and easily to raise your vibration and enhance your psychic abilities?
Please check my poster below for more details, I am looking forward to seeing you there.
- To book a healing session, please click here.
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- To book a TCM treatment, please click here.
- To book a group session for a variety of topics, please click here.
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